The Vocalibrate dictionary

deleterious

US/ˌdɛləˈtɪriəs/GB/ˌdɛlɪˈtɪəriəs/adjective

harmful or damaging

Lack of sleep has a deleterious effect on memory.

Near in meaning
harmfuldamagingdetrimentalinjurious
In the family
deleteriouslydeleteriousness

More words worth knowing